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Leukeran: Overview, Uses, and Active Ingredient

What is Leukeran?

Leukeran is a chemotherapy drug that contains chlorambucil as its active ingredient. It is primarily used to treat chronic lymphocytic leukemia, Hodgkin's lymphoma, non-Hodgkin's lymphoma, and other types of cancer.

Description of the Drug

Leukeran is available in tablet form and is taken orally. Each tablet contains 2 mg of chlorambucil. It is available in bottles of 30 tablets and 100 tablets.

Pharmacological Action

Leukeran works by interfering with the DNA in cancer cells, preventing them from multiplying and spreading throughout the body. It also suppresses the immune system, which can be helpful in treating certain types of cancer.

Dosage and Administration

The dosage of Leukeran varies depending on the type of cancer being treated, the patient's age and weight, and other factors. The medication should be taken exactly as prescribed by the doctor.

Precautions and Contraindications

Leukeran should not be taken by pregnant or breastfeeding women, as it can harm the fetus or baby. Patients with kidney or liver disease should use this medication with caution, and those with a history of bone marrow suppression should be closely monitored.

Side Effects

Common side effects of Leukeran include nausea, vomiting, diarrhea, fatigue, and hair loss. It can also cause more serious side effects, such as infection, bleeding, and an increased risk of developing other types of cancer.

Interaction with Other Medications

Leukeran can interact with other medications, including certain antibiotics and vaccines. Patients should inform their doctor of all medications and supplements they are taking before starting Leukeran.

Overdose and Analogues

Overdose of Leukeran can cause severe side effects, including bone marrow suppression and kidney or liver damage. In case of overdose, patients should seek immediate medical attention. Analogues of Leukeran include Bendamustine and Fludarabine.

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Disclaimer: The information provided above is for informational purposes only and should not be used as a substitute for professional medical advice. Always consult your doctor before taking any medication or changing your treatment plan.