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What is Glucophage and How is it Used for Treatment?

Glucophage is a medication used to treat type 2 diabetes. It contains the active ingredient metformin hydrochloride, which helps to lower blood sugar levels by reducing the amount of glucose produced by the liver and improving insulin sensitivity in the body.

Description

Glucophage is available in tablet form, and each tablet contains 500mg or 850mg of metformin hydrochloride as the active ingredient. The tablets are white, film-coated, and oblong-shaped. The tablets come in blister packs of 30 or 60 tablets and are also available in bottles of 100 tablets.

Pharmacological Action

Metformin hydrochloride is an oral antidiabetic agent that improves glucose tolerance in patients with type 2 diabetes. It reduces hepatic glucose production and increases insulin sensitivity in peripheral tissue, thereby improving glucose uptake and utilization. Metformin also decreases intestinal absorption of glucose and reduces appetite.

Dosage

The recommended starting dose of Glucophage is 500mg twice daily or 850mg once daily with meals. The maximum daily dose is 2550mg. The dosage may be increased gradually based on blood glucose levels.

Precautions

Glucophage should be used with caution in patients with liver or kidney disease, heart failure, or who are alcoholics. It should not be used in patients with severe dehydration, severe infection, or who are undergoing surgery. Patients taking Glucophage should have their kidney function monitored regularly.

Contraindications

Glucophage is contraindicated in patients with a hypersensitivity to metformin hydrochloride or any of the tablet's components. It should not be used in patients with severe renal impairment (eGFR

Side Effects

Common side effects of Glucophage include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects usually resolve within a few days of starting the medication. Rare but serious side effects include lactic acidosis, a condition that can be fatal if not treated promptly.

Interaction with Other Medications

Glucophage may interact with other medications, including cimetidine, furosemide, nifedipine, and certain beta-blockers. Patients should inform their healthcare provider about all medications they are taking before starting Glucophage.

Overdose

Overdose of Glucophage can cause lactic acidosis, which can be fatal if not treated promptly. Symptoms of lactic acidosis include abdominal pain, rapid breathing, muscle pain, and confusion. If you suspect an overdose, seek medical attention immediately.

Analogs

There are several other medications available that contain metformin hydrochloride as the active ingredient, including Glumetza, Fortamet, and Riomet.

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Disclaimer

The information provided in this article is for informational purposes only and is not intended as a substitute for advice from your healthcare provider or pharmacist. Always consult your healthcare provider or pharmacist before taking any medication or making any changes to your healthcare regimen. Alldiscountpills.com is not responsible for any errors or omissions in the information provided.