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Furadantin: What It Is and How It Works

What is Furadantin?

Furadantin is a medication that belongs to the class of drugs known as nitrofurans. It is primarily used to treat bacterial infections of the urinary tract, including cystitis, pyelonephritis, and urethritis.

Active Ingredient

The active ingredient in Furadantin is nitrofurantoin. This is a synthetic antimicrobial agent that works by inhibiting the bacterial enzyme system that is responsible for the synthesis of bacterial cell walls and proteins.

Detailed Description of Furadantin

Description

Furadantin is an oral medication that is available in capsule form. Each capsule contains 50mg of nitrofurantoin. The capsules are opaque, yellow and grey in color, and imprinted with the letters "F" and "N" on each half of the capsule.

Packaging and Composition

Furadantin is available in plastic bottles containing 100 capsules each. The capsules are packed in a protective sleeve to ensure their integrity. The composition of each capsule includes 50mg of nitrofurantoin, as well as other inactive ingredients such as maize starch, lactose, magnesium stearate, and gelatin.

Pharmacological Action

Furadantin has a broad-spectrum antimicrobial action against most gram-positive and gram-negative bacteria, as well as some fungi. It works by inhibiting bacterial cell wall synthesis and protein synthesis. Nitrofurantoin is also excreted in the urine, which enhances its efficacy in treating urinary tract infections.

Dosage and Administration

The recommended dosage for Furadantin is 50mg to 100mg four times a day, taken with food or milk. The duration of treatment varies depending on the severity and type of infection, but typically lasts for 7 to 10 days.

Precautions and Contraindications

Furadantin is contraindicated in patients with a history of hypersensitivity to nitrofurantoin or any of its inactive ingredients. It should also not be used in patients with renal impairment or oliguria, or in pregnant women near term (38-42 weeks) of pregnancy. The drug should be used with caution in patients with hepatic or pulmonary disease, anemia, diabetes, or electrolyte imbalance.

Side Effects

The most common side effects associated with Furadantin include nausea, vomiting, diarrhea, abdominal pain, and headache. Other possible side effects include dizziness, drowsiness, skin rash, itching, and fever. In rare cases, the medication can cause severe allergic reactions, such as anaphylaxis, which requires immediate medical attention.

Drug Interactions

Furadantin can interact with several medications, including probenecid, sulfinpyrazone, and oral anticoagulants. Patients taking these medications should be monitored carefully for signs of toxicity or reduced efficacy.

Overdose

In the event of an overdose, patients may experience symptoms such as vomiting, abdominal pain, and diarrhea. Treatment may include gastric lavage, administration of activated charcoal, and supportive measures such as intravenous fluids and electrolyte replacement.

Analogs

Furadantin is a branded medication, and there are several generic versions available on the market. Some of the generic versions of Furadantin include Nitrofurantoin Macrocrystals, Nitrofurantoin Monohydrate, and Furadantin Retard.

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Disclaimer: The information provided here is for educational purposes only and should not be used as a substitute for professional medical advice. Always consult your healthcare provider before taking any medication. AllDiscountPills.com does not endorse or promote any medication or treatment mentioned in this article. The website is not responsible for any damages or losses that may arise from the use of the information provided here.