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Flibanserin: A Women’s Medicine for Sexual Dysfunction

What is Flibanserin?

Flibanserin is a prescription medicine used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. HSDD is a medical condition that causes a persistent or recurrent absence of sexual thoughts, fantasies, and desire for sexual activity that causes significant distress or interpersonal difficulty.

Active Ingredient

Flibanserin is the active ingredient in the medicine. It works by increasing levels of dopamine and norepinephrine while decreasing serotonin in the brain, which can help improve sexual desire and arousal.

Product Description

Flibanserin is available in tablet form and is taken orally with or without food. The tablet should be swallowed whole and should not be crushed, chewed, or split. Each tablet contains 100mg of flibanserin.

Packaging and Composition

Flibanserin is available in packs of 10 or 30 tablets. The tablets are white to off-white, round, and film-coated. The composition of the tablet includes microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate, hypromellose, titanium dioxide, and polyethylene glycol.

Pharmacological Action

Flibanserin is a selective serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist. It works by increasing levels of dopamine and norepinephrine while decreasing serotonin in the brain, which can help improve sexual desire and arousal.

Dosage and Administration

The recommended dose of Flibanserin is one tablet (100mg) taken once daily at bedtime. The medicine should be taken only by women who have been diagnosed with HSDD.

Precautions and Contraindications

Flibanserin should not be taken by pregnant women or women who are breastfeeding. The medicine should also not be taken with alcohol as it can increase the risk of hypotension and syncope. Flibanserin should not be taken by individuals with severe hepatic impairment or with concomitant use of CYP3A4 inhibitors.

Side Effects

The common side effects of Flibanserin include dizziness, somnolence, nausea, fatigue, insomnia, and dry mouth. These side effects usually resolve within 2-3 weeks of starting the medicine.

Interactions with Other Medications

Flibanserin can interact with medications that are metabolized by CYP3A4, such as ketoconazole, clarithromycin, and ritonavir. Flibanserin can also interact with alcohol and other central nervous system depressants, such as benzodiazepines and opioids.

Overdose

In case of an overdose of Flibanserin, the individual should seek medical attention immediately. Symptoms of an overdose include hypotension, syncope, and CNS depression.

Analogues

The analogues of Flibanserin include Bremelanotide, Addyi, and Intrinsa.

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Disclaimer: This article is for informational purposes only and should not be used as a substitute for medical advice. Please consult your healthcare provider before taking any medication.