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Feldene: Uses, Composition, and Dosage

What is Feldene?

Feldene is a non-steroidal anti-inflammatory drug (NSAID) that contains piroxicam as its active ingredient. It is used to relieve pain and inflammation in conditions such as arthritis, osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Description

Feldene is available in the form of capsules and comes in different strengths, including 10 mg and 20 mg. Each capsule contains piroxicam, which is a non-steroidal anti-inflammatory drug that works by blocking the production of prostaglandins, which are responsible for inflammation, pain, and fever in the body.

Pharmacological Action

Feldene belongs to the class of non-steroidal anti-inflammatory drugs and has analgesic, anti-inflammatory, and antipyretic effects. It works by inhibiting the production of prostaglandins, which are involved in the inflammatory process. By blocking the production of prostaglandins, Feldene helps to reduce pain, inflammation, and fever in the body.

Dosage and Administration

The recommended dosage of Feldene is 20 mg per day, taken as a single dose or in two divided doses. The maximum daily dose should not exceed 40 mg per day. Feldene should be taken with food or milk to reduce the risk of gastrointestinal side effects. The duration of treatment depends on the condition being treated and should be determined by a healthcare professional.

Precautions and Contraindications

Feldene should be used with caution in patients with a history of gastrointestinal bleeding, ulceration, or perforation, as it may exacerbate these conditions. It should not be used in patients with severe hepatic or renal impairment, as it may increase the risk of adverse effects. Feldene should be used with caution in patients with a history of cardiovascular disease, as it may increase the risk of cardiovascular events.

Side Effects

The most common side effects of Feldene include gastrointestinal effects, such as nausea, vomiting, diarrhea, and abdominal pain. Other side effects may include headache, dizziness, and rash. In rare cases, Feldene may cause serious side effects, such as gastrointestinal bleeding or ulceration, liver damage, and kidney damage.

Interaction with Other Drugs

Feldene may interact with other drugs, including aspirin, other non-steroidal anti-inflammatory drugs, anticoagulants, and corticosteroids. These interactions may increase the risk of adverse effects and should be avoided.

Overdose

In case of overdose, the patient should seek medical attention immediately. The symptoms of overdose may include gastrointestinal bleeding, kidney failure, and liver damage.

Analogues

There are several analogues of Feldene, including Ibuprofen, Naproxen, and Diclofenac. These drugs have similar pharmacological properties and are used to treat similar conditions.

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Disclaimer

The information provided here is for informational purposes only and is not intended to replace the advice of a healthcare professional. Always consult your healthcare professional before taking any medication.