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Diltiazem: Uses, Composition, and Pharmacological Effects

What is Diltiazem?

Diltiazem is a medication that belongs to a class of drugs known as calcium channel blockers. It is used to treat high blood pressure, chest pain (angina), and certain heart rhythm disorders.

Active Ingredient

The active ingredient in Diltiazem is diltiazem hydrochloride. This compound is a white crystalline powder that is soluble in water and ethanol.

Dosage and Administration

Diltiazem is available in several forms, including tablets, capsules, and injectable solutions. The dose and duration of treatment depend on the patient's condition and response to therapy.

Pharmacological Effects

Diltiazem works by blocking the influx of calcium ions into the cells of the heart and blood vessels, leading to relaxation of the smooth muscle and vasodilation. This helps to reduce blood pressure, improve blood flow, and decrease the workload on the heart.

Precautions and Contraindications

Diltiazem is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It should be used with caution in patients with liver or kidney disease, heart failure, or low blood pressure.

Side Effects

The most common side effects of Diltiazem include headache, dizziness, nausea, flushing, and constipation. More serious side effects, such as chest pain, irregular heartbeat, and difficulty breathing, should be reported to a doctor immediately.

Interaction with Other Drugs

Diltiazem may interact with several other medications, including beta-blockers, digoxin, and statins. Patients should inform their doctor of all medications they are taking before starting Diltiazem.

Overdose

In the event of an overdose, immediate medical attention is necessary. Symptoms of overdose may include dizziness, fainting, and difficulty breathing.

Analogs

There are several analogs of Diltiazem available, including Verapamil, Nifedipine, and Amlodipine.

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is great, and the prices can't be beat." Disclaimer: The information provided in this article is for educational purposes only and is not intended to replace medical advice. Always consult with a healthcare provider before starting or stopping any medication.