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Cymbalta: What It Is and How It's Used

Overview

Cymbalta is a medication used to treat depression, anxiety, and pain disorders such as fibromyalgia and diabetic neuropathy. Its active ingredient is duloxetine, a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that works by increasing the levels of these neurotransmitters in the brain.

Description and Packaging

Cymbalta comes in the form of delayed-release capsules in doses of 20mg, 30mg, and 60mg. The capsules are opaque, blue and green, and have the strength imprinted on them. They are packaged in blister packs and bottles of 30 or 90 capsules.

Pharmacological Action and Dosage

Cymbalta's dual action on serotonin and norepinephrine can improve mood, relieve anxiety, and reduce pain perception. The recommended starting dose is 60mg once daily, taken with or without food. Depending on the patient's response, the dose may be increased or decreased, but should not exceed 120mg per day. It may take several weeks to see the full therapeutic effect of Cymbalta.

Precautions and Contraindications

Cymbalta is not suitable for everyone. It should not be taken by those who are allergic to duloxetine or have taken a monoamine oxidase inhibitor (MAOI) in the past 14 days. It should also not be taken by those with liver or kidney disease, uncontrolled narrow-angle glaucoma, or a history of seizures. Cymbalta can interact with other medications, so it's important to tell your doctor about all medications you are taking before starting Cymbalta.

Side Effects and Overdose

Common side effects of Cymbalta include nausea, dry mouth, dizziness, and fatigue. In rare cases, it may cause suicidal thoughts, especially in young adults. In the event of an overdose, seek medical attention immediately. Symptoms may include seizures, irregular heartbeat, and respiratory distress.

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