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What is Asacol?
Asacol (Mesalamine) is a medication used to treat ulcerative colitis and other inflammatory bowel diseases. It works by reducing inflammation in the colon.
Formulation and Packaging
Asacol is available in the form of tablets. Each tablet contains 400mg of Mesalamine. The tablets are packed in blister packs of 10 tablets each.
Pharmacological Action
Asacol (Mesalamine) works by reducing inflammation in the colon. It is a 5-aminosalicylic acid (5-ASA) drug that is believed to work by blocking the production of certain chemicals in the body that cause inflammation. Asacol is only effective in treating inflammation in the colon and is not effective in treating inflammation elsewhere in the body.
Dosage and Administration
The dosage of Asacol (Mesalamine) varies depending on the severity of the condition being treated. The usual recommended dose for adults with ulcerative colitis is 800mg three times a day for a total of 2.4g per day. The tablets should be swallowed whole and should not be crushed or chewed.
Precautions
Asacol (Mesalamine) should be used with caution in patients with kidney problems. It should not be used in patients with a history of allergic reactions to salicylates, sulfasalazine, or any other component of the medication. Asacol should also be used with caution in patients with liver problems or a history of liver disease.
Contraindications
Asacol (Mesalamine) is contraindicated in patients with a history of hypersensitivity to salicylates or aminosalicylates, as well as in patients with severe liver or kidney disease.
Side Effects
The most common side effects of Asacol (Mesalamine) are headache, nausea, vomiting, diarrhea, abdominal pain, and gas. In rare cases, Asacol may cause severe allergic reactions, which require immediate medical attention.
Drug Interactions
Asacol (Mesalamine) may interact with other medications such as azathioprine, mercaptopurine, and warfarin. Patients should inform their healthcare provider of all medications they are taking before starting Asacol.
Overdose
In case of overdose, patients should seek immediate medical attention. Symptoms of an Asacol overdose may include ringing in the ears, confusion, seizures, and coma.
Analogs
Some analogs of Asacol (Mesalamine) include Pentasa, Rowasa, and Canasa.
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