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Aricept: Detailed Instructions for Use

What is Aricept?

Aricept is a medication used to treat the symptoms of Alzheimer's disease. It belongs to a group of drugs known as cholinesterase inhibitors, which work by increasing the levels of a certain neurotransmitter in the brain called acetylcholine.

Form and Packaging

Aricept comes in tablet form and is available in strengths of 5mg, 10mg, and 23mg. The tablets are white, round, and film-coated, and they are imprinted with "Aricept" and the strength on one side.

The tablets are packaged in blister packs containing 28 tablets each. They are also available in bottles containing 30 tablets each.

Pharmacological Action

Aricept works by inhibiting the activity of an enzyme called acetylcholinesterase, which breaks down acetylcholine. This leads to an increase in the amount of acetylcholine available in the brain, which can help to improve cognitive function in patients with Alzheimer's disease.

Dosage and Administration

The recommended starting dose of Aricept is 5mg once daily. After 4-6 weeks, the dose may be increased to 10mg once daily if tolerated. The maximum recommended dose is 23mg once daily.

Aricept should be taken at bedtime, with or without food.

Precautions

Before taking Aricept, patients should inform their doctor if they have any allergies, liver disease, or heart rhythm problems. They should also inform their doctor of any medications they are taking, as some drugs can interact with Aricept.

Aricept can cause dizziness or drowsiness, so patients should avoid driving or operating machinery until they know how the medication affects them.

Contraindications

Aricept is contraindicated in patients who are allergic to the active ingredient, donepezil, or any other ingredients in the medication.

Side Effects

The most common side effects of Aricept include nausea, vomiting, diarrhea, loss of appetite, and muscle cramps. These side effects are usually mild and go away on their own, but patients should inform their doctor if they are persistent or bothersome.

Drug Interactions

Aricept can interact with several medications, including ketoconazole, quinidine, and certain antidepressants. Patients should inform their doctor of all medications they are taking before starting Aricept.

Overdose

In the event of an overdose, patients should seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, drooling, sweating, slow heart rate, and fainting.

Analogues

Some analogues of Aricept include Exelon (rivastigmine), Razadyne (galantamine), and Namenda (memantine).

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