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What is Arava?

Arava (leflunomide) is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and other autoimmune diseases. It works by reducing inflammation and slowing down the progression of the disease.

Description and Packaging

Arava is available in tablet form and comes in a blister pack of 30 tablets. Each tablet contains 10mg or 20mg of leflunomide. The tablets are film-coated and are yellow in color.

Pharmacological Action

Arava works by inhibiting the production of certain immune cells that are responsible for causing inflammation in the joints. This helps to reduce pain and swelling, and it slows down the progression of the disease. It can take several weeks or months to see the full effects of Arava, so it is important to continue taking the medication as directed.

Dosage and Administration

The recommended dose of Arava for adults with rheumatoid arthritis is 100mg once daily for the first three days, followed by 20mg once daily thereafter. For adults with psoriatic arthritis, the recommended dose is 20mg once daily. Arava should be taken with food and should be swallowed whole with a full glass of water.

Precautions and Contraindications

Arava should not be taken by pregnant women, as it can cause birth defects. It should also not be taken by individuals with liver disease or a history of hepatitis. Before taking Arava, inform your doctor if you have any other medical conditions, are taking any other medications, or have any allergies.

Side Effects and Interactions

The most common side effects of Arava include nausea, diarrhea, hair loss, and skin rash. Arava may interact with other medications, including warfarin, methotrexate, and theophylline. Be sure to inform your doctor of all medications you are taking before starting Arava.

Overdose and Analogues

If you suspect an overdose of Arava, seek medical attention immediately. There are no specific antidotes for Arava overdose, but treatment may involve activated charcoal, gastric lavage, and supportive measures. There are no exact analogues for Arava, but other medications used to treat rheumatoid arthritis include methotrexate, hydroxychloroquine, and sulfasalazine.

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