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What is Aralen?

Aralen (chloroquine) is a medication used to prevent and treat malaria. It works by killing the parasites that cause the disease. Aralen is also sometimes used to treat certain autoimmune disorders, such as lupus and rheumatoid arthritis. It is available in tablet form.

Formulation and Packaging

Aralen is available in tablet form. Each tablet contains 250mg of chloroquine phosphate. The tablets are round, white, and scored. Aralen is available in blister packs of 10 tablets each, and each pack is wrapped in a foil pouch to protect the medication from light and moisture.

Pharmacological Action

Aralen works by interfering with the DNA of the malaria parasite, preventing it from reproducing and eventually killing it. It also has anti-inflammatory properties, which make it useful in the treatment of autoimmune disorders. Aralen is absorbed quickly and extensively from the gastrointestinal tract and distributed throughout the body, including to the liver, spleen, kidneys, and lungs.

Dosage and Administration

The dosage of Aralen depends on the condition being treated and the patient's weight. For the treatment of malaria, the usual adult dose is 500mg (2 tablets) taken once a week, starting 1 to 2 weeks before entering the malaria-endemic area and continuing for 4 to 8 weeks after leaving the area. For the treatment of autoimmune disorders, the dosage may be higher and may be taken daily or every other day. It is important to follow your healthcare provider's instructions carefully.

Precautions and Contraindications

Aralen should not be taken by individuals who are allergic to chloroquine or any of its ingredients. It should also not be taken by individuals with a history of vision problems or hearing loss, liver or kidney disease, or certain blood disorders. Aralen may interact with other medications, so it is important to inform your healthcare provider of all medications you are taking. Aralen should be used with caution in individuals with psoriasis, porphyria, or myasthenia gravis. It is important to discuss your medical history with your healthcare provider before taking Aralen.

Side Effects

The most common side effects of Aralen include headache, nausea, diarrhea, stomach pain, and itching. These side effects are usually mild and go away on their own. However, more serious side effects, such as vision changes, hearing loss, and muscle weakness, can occur. If you experience any of these side effects, it is important to contact your healthcare provider immediately.

Interaction with Other Medications

Aralen may interact with other medications, including other antimalarial medications, antibiotics, and certain medications used to treat heart rhythm problems. It is important to inform your healthcare provider of all medications you are taking before starting Aralen.

Overdose

Overdose of Aralen can cause serious side effects, including seizures, cardiac arrest, and respiratory depression. If you suspect an overdose, it is important to seek medical attention immediately.

Analogs

Aralen has several analogs, including hydroxychloroquine (Plaquenil) and quinacrine (Atabrine). These medications work in a similar way to Aralen and may be used to treat the same conditions.

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