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What is Avapro?
Avapro is a medication used to treat high blood pressure (hypertension) and diabetic nephropathy. It belongs to a class of drugs called angiotensin receptor blockers (ARBs) and works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow.
Description
Avapro is available in tablet form for oral administration. Each tablet contains 75mg, 150mg, or 300mg of irbesartan, the active ingredient in Avapro. The tablets also contain various inactive ingredients such as microcrystalline cellulose, croscarmellose sodium, and magnesium stearate.
Pharmacological Action
Avapro blocks the action of angiotensin II, a hormone that causes blood vessels to constrict. By blocking the action of this hormone, Avapro helps to widen blood vessels, reducing blood pressure and improving blood flow.
Dosage and Administration
The recommended starting dose of Avapro for adults is 150mg once daily. The dose may be increased to 300mg once daily if necessary. Avapro can be taken with or without food, but should be taken at the same time each day.
Precautions and Contraindications
Avapro should not be used by pregnant women, as it may harm the fetus. It should also not be used in patients with severe kidney disease, or in patients who are allergic to irbesartan or any other ingredients in Avapro. Patients with liver disease should use Avapro with caution, as it may increase the risk of liver problems.
Side Effects
Common side effects of Avapro include dizziness, nausea, and tiredness. More serious side effects include kidney problems, high potassium levels, and allergic reactions. If you experience any of these side effects, seek medical attention immediately.
Interactions
Avapro may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), potassium supplements, and certain diuretics. It is important to tell your doctor about all medications you are taking before starting Avapro.
Overdose
If you suspect an overdose of Avapro, seek medical attention immediately. Symptoms of overdose may include dizziness, fainting, and rapid heartbeat.
Analogues
There are several other medications in the same class as Avapro, including losartan, candesartan, and valsartan.
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