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What is Anafranil?

Anafranil is a tricyclic antidepressant that is used to treat depression, obsessive-compulsive disorder (OCD), and other mental health conditions. It works by increasing the levels of certain chemicals in the brain that affect mood and behavior.

Description

Anafranil is available in the form of tablets. The tablets are round, yellow, film-coated, and engraved with "ANA 10" on one side and a Greek alpha symbol on the other. Each tablet contains 10 mg of clomipramine hydrochloride.

Packaging and Composition

Anafranil is available in blister packs of 30 tablets. The composition of each tablet is as follows:

• Active ingredient: clomipramine hydrochloride
• Inactive ingredients: microcrystalline cellulose, lactose monohydrate, maize starch, colloidal anhydrous silica, magnesium stearate, hypromellose, macrogol 4000, titanium dioxide (E171), quinoline yellow (E104), and sunset yellow (E110).

Pharmacological Action

Anafranil works by inhibiting the reuptake of serotonin and norepinephrine in the brain. This results in increased levels of these neurotransmitters, which help to regulate mood and behavior. The medication also has anticholinergic and sedative properties.

Dosage

The dosage of Anafranil depends on the condition being treated and the patient's individual response to the medication. The recommended starting dose for adults is 25 mg per day, taken in divided doses. The dose may be gradually increased by 25 mg every few days until the desired response is achieved. The maximum daily dose is 250 mg.

Precautions

Before taking Anafranil, inform your doctor if you have any medical conditions, including heart disease, liver or kidney disease, seizures, or glaucoma. It is important to inform your doctor of all medications you are taking, including over-the-counter medications and herbal supplements, as they may interact with Anafranil.

Contraindications

Do not take Anafranil if you are allergic to clomipramine or any other ingredients in the medication. The medication should also not be taken with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOIs.

Side Effects

The most common side effects of Anafranil include dry mouth, constipation, blurred vision, dizziness, drowsiness, weight gain, and sexual dysfunction. Less common side effects include seizures, hallucinations, and suicidal thoughts or behaviors. If you experience any of these side effects, contact your doctor immediately.

Drug Interactions

Anafranil may interact with other medications, including other antidepressants, antihistamines, antipsychotics, and medications that affect heart rhythm. Inform your doctor of all medications you are taking before starting Anafranil to avoid any potential drug interactions.

Overdose

If you suspect an overdose of Anafranil, seek medical attention immediately. Symptoms of an overdose may include confusion, hallucinations, seizures, irregular heartbeat, and coma.

Anafranil Analogs

There are several analogs of Anafranil available, including imipramine, amitriptyline, and doxepin. These medications are also tricyclic antidepressants and work in a similar way to Anafranil. However, they may have different dosages and side effects, so it is important to consult with your doctor before switching to an analog medication.

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